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Geometrical Considerations in Patient Specific Models of a Human Aorta with Stenosis and Aneurysm
Linköping University, Department of Mechanical Engineering. Linköping University, The Institute of Technology.
Linköping University, Department of Mechanical Engineering. Linköping University, The Institute of Technology.
Linköping University, Department of Biomedical Engineering. Linköping University, The Institute of Technology.ORCID iD: 0000-0001-5526-2399
2004 (English)In: Computational Fluid Dynamics 2004: Proceedings of the Third International Conference on Computational Fluid Dynamics, ICCFD3, Toronto, 12–16 July 2004, 2004, 335-340 p.Conference paper, Published paper (Refereed)
Abstract [en]

The most important artery in the human body is the aorta that supplies the rest of the body with blood. Lesions in the aorta can cause serious complications, which can even lead to death. How the flow is behaving in lesions, what causes the problems and which lesions are dangerous are highly interesting to determine. Laminar, stationary CFD calculations are performed on two geometrically different models of the human aorta created from the same set of patient MRI (Magnetic Resonance Imaging) data. Differences in the CFD results due to different geometries are evaluated. Overview results e.g. pressure variations throughout the artery are not dependent on an exact description of the geometry. If absolute and local values e.g. wall shear stress are sought more robust geometry creation procedure is needed in order to get more reliable results.

Place, publisher, year, edition, pages
2004. 335-340 p.
Keyword [en]
Geometrical considertions, Human Aorta
National Category
Engineering and Technology
Identifiers
URN: urn:nbn:se:liu:diva-23244DOI: 10.1007/3-540-31801-1_46Local ID: 2661ISBN: 978-3-540-31800-2 (print)OAI: oai:DiVA.org:liu-23244DiVA: diva2:243558
Conference
Third International Conference on Computational Fluid Dynamics, ICCFD3, Toronto, 12–16 July 2004
Available from: 2009-10-07 Created: 2009-10-07 Last updated: 2016-03-14
In thesis
1. Estimating patient specific wall shear stress in the human aorta: geometrical and post-processing considerations
Open this publication in new window or tab >>Estimating patient specific wall shear stress in the human aorta: geometrical and post-processing considerations
2006 (English)Licentiate thesis, comprehensive summary (Other academic)
Abstract [en]

This thesis describes a workflow to perform in-vivo wall shear stress (WSS) estimations in the human aorta using computational fluid dynamics (CFD) methods. An abnormal WSS distribution is believed to influence the development of many cardiovascular diseases, e.g. atherosclerosis. The focus in this thesis is on geometrical influence on the WSS results and interpretation methods tor non-stationary results. The work shows that results are sensitive to the choice of segmentation method (the process from medical images to a geometrical model) and a correct geometrical description of the artery is crucial in making WSS estimations. A new parameter for non-stationary WSS results has been proposed; Wall Shear Stress Angular Amplitude (WSSAA), making the analysis of non-stationary results more straight-forward. It has been shown that the workfiow can be used with confidence and that WSS can be estimated in-vivo. using the combination of MRI-based geometry definition and CFD.

Place, publisher, year, edition, pages
Linköping: Linköpings universitet, 2006. 29 p.
Series
Linköping Studies in Science and Technology. Thesis, ISSN 0280-7971 ; 1275
National Category
Engineering and Technology
Identifiers
urn:nbn:se:liu:diva-36904 (URN)32991 (Local ID)91-85643-75-0 (ISBN)32991 (Archive number)32991 (OAI)
Available from: 2009-10-10 Created: 2009-10-10 Last updated: 2013-12-19

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Svensson, JohanGårdhagen, RolandKarlsson, Matts

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CiteExportLink to record
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Citation style
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