Photon pathlength determination based on spatially resolved diffuse reflectance
2002 (English)In: Journal of Biomedical Optics, ISSN 1083-3668, Vol. 7, no 3, 478-485 p.Article in journal (Refereed) Published
A method for the prediction of the average photon pathlength in turbid media has been developed. The method is based on spatially resolved diffuse reflectance with discrete source detector distances up to 2 mm. Light reflectance was simulated using a Monte Carlo technique with a one-layer model utilizing a wide range of optical properties, relevant to human skin. At a source detector separation of 2 mm, the pathlength can vary sixfold due to differences in optical properties. By applying various preprocessing and prediction techniques, the pathlength can be predicted with a root-mean-square error of approximately 5%. Estimation of the photon pathlength can be used, e.g., to remove the influence of optical properties on laser Doppler flowmetry perfusion readings, which are almost linearly related to the average photon pathlength.
Place, publisher, year, edition, pages
2002. Vol. 7, no 3, 478-485 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-24559DOI: 10.1117/1.1482378Local ID: 6721OAI: oai:DiVA.org:liu-24559DiVA: diva2:244880