Pigment epithelial changes in a strain of pigmented rabbits with low ERG b-wave amplitudes
2004 (English)In: Vision Research, ISSN 0042-6989, Vol. 44, no 1, 99-102 p.Article in journal (Refereed) Published
Retinas from a strain of rabbits with low dark-adapted electroretinographic (ERG) b-wave amplitudes, and declining ERG responses with time, were examined by light and electron microscopy. Seven rabbits from the affected strain (13 months to 5 years old) and six control animals (6-26 months old) were included in the study. Small inclusions with an electron dense border, about 0.2-1.5 μm in diameter, were significantly (p<0.01) more numerous within the retinal pigment epithelial (RPE) cells in the affected rabbits than in the control animals. No morphological evidence of retinal degeneration was found. Further studies are needed to establish the functional defect in this strain of rabbits.
Place, publisher, year, edition, pages
2004. Vol. 44, no 1, 99-102 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-24729DOI: 10.1016/j.visres.2003.08.003Local ID: 6979OAI: oai:DiVA.org:liu-24729DiVA: diva2:245052