liu.seSearch for publications in DiVA
Change search
ReferencesLink to record
Permanent link

Direct link
Morphology of early developing oligodendrocytes in the ventrolateral spinal cord of the chicken
Linköping University, Department of Biomedicine and Surgery, Cell biology. Linköping University, Faculty of Health Sciences.
2003 (English)In: Journal of Neurocytology, ISSN 0300-4864, E-ISSN 1573-7381, Vol. 32, no 9, 1045-1053 p.Article in journal (Refereed) Published
Abstract [en]

The oligodendroglial population includes Type I and II cells related to several thin axons, Type III cells with a few processes in relation to relatively thick axons and Type IV cells related to a single thick axon. This structural diversity of oligodendrocytes is accompanied by a molecular heterogeneity. In the chicken spinal cord, oligodendrocytes have begun to contact axons at embryonic day (E)10 and compact sheaths have appeared by E12. At the latter stage, most sheath-forming oligodendrocytes contact more than one axon. At E15, however, each sheath-forming cell seems to have developed a Schwann cell-like anatomy, being related to a single axon. Based on these findings, the present study examines more thoroughly the anatomy of early developing oligodendrocytes in the chicken spinal cord. Examination of slices immunostained with antibodies against the oligodendroglial marker O4 showed that a few positive cells are present at E6, after which the occurrence increases with age. At E12 most immunostained cells have two or more processes. At E15 however, dye-injected oligodendrocytes have developed a Type IV structure. Between E12 and E15, mean sheath length increases about 4×, from 50 µm to over 200 µm, while the length of the spinal cord increases 36% only. This indicates that early oligodendrocytes in chicken white matter develop a Type IV anatomy between E12 and E15 through an elimination of sheaths.

Place, publisher, year, edition, pages
2003. Vol. 32, no 9, 1045-1053 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-24855DOI: 10.1023/B:NEUR.0000021901.27596.97Local ID: 9255OAI: diva2:245178
Available from: 2009-10-07 Created: 2009-10-07 Last updated: 2012-09-21Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Anderson, Emma S.
By organisation
Cell biologyFaculty of Health Sciences
In the same journal
Journal of Neurocytology
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 27 hits
ReferencesLink to record
Permanent link

Direct link