Synthesis of inositol phosphoglycans containing thiol-terminated spacers for efficient coupling to maleimide functionalized solid phases or proteins
2002 (English)In: Tetrahedron, ISSN 0040-4020, Vol. 58, no 21, 4245-4254 p.Article in journal (Refereed) Published
The synthesis of inositol phosphoglycans (IPGs), analogous to second messengers of insulin, to provide a small targeted library of compounds is described. These derivatives contain the glucosamine(a1-6)myo-inositol 1,2-cyclic phosphate motif. A thiol-terminated spacer was introduced, for their immobilization, by a radical elongation of an allyl ether with benzyl mercaptane. ⌐ 2002 Elsevier Science Ltd. All rights reserved.
Place, publisher, year, edition, pages
2002. Vol. 58, no 21, 4245-4254 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-25385DOI: 10.1016/S0040-4020(02)00359-9Local ID: 9828OAI: oai:DiVA.org:liu-25385DiVA: diva2:245714