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Cytokines in breast milk from allergic and nonallergic mothers
Linköping University, Department of Molecular and Clinical Medicine, Pediatrics. Linköping University, Faculty of Health Sciences.
Linköping University, Department of Molecular and Clinical Medicine, Pediatrics. Linköping University, Faculty of Health Sciences.
Department of Pediatrics, Division of Immunology/Allergy/Rheumatology, Galveston, Tex., USA.
Linköping University, Department of Molecular and Clinical Medicine, Pediatrics. Linköping University, Faculty of Health Sciences.
1999 (English)In: International Archives of Allergy and Immunology, ISSN 1018-2438, E-ISSN 1423-0097, Vol. 118, no 2-4, 319-320 p.Article in journal (Refereed) Published
Abstract [en]

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The allergy–preventing effect of breast–feeding is controversial [1, 2]. This may be due to individual variations of the composition of human milk. Allergy is associated with a bias to production of cytokines involved in IgE synthesis, e.g. IL–4 and IL–13 [3] and the eosinophil chemotactic [4] and survival [5] factor IL–5. In contrast, IFN–=γ, which inhibits IgE synthesis [6], is downregulated [7]. Cytokines involved in IgA production, IL–6, IL–10 and TGF–β [8, 9] have also been proposed to be involved in IgE synthesis [10, 11, 12].

Place, publisher, year, edition, pages
1999. Vol. 118, no 2-4, 319-320 p.
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-25826DOI: 10.1159/000024117Local ID: 10263OAI: oai:DiVA.org:liu-25826DiVA: diva2:246374
Available from: 2009-10-08 Created: 2009-10-08 Last updated: 2017-12-13Bibliographically approved

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Fagerås Böttcher, MalinJenmalm, MariaBjörkstén, Bengt

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