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Ultrasound determined carotid and femoral atherosclerosis in Lithuanian and Swedish men: The LiVicordia study
Linköping University, Faculty of Health Sciences. Linköping University, Department of health and environment. Östergötlands Läns Landsting, FHVC - Folkhälsovetenskapligt centrum, Förebygg.med.
Linköping University, Faculty of Health Sciences. Linköping University, Department of Medicine and Care, Clinical Physiology. Östergötlands Läns Landsting, Heart Centre, Department of Clinical Physiology.
Linköping University, Faculty of Health Sciences. Linköping University, Department of Medicine and Care, Cardiology. Östergötlands Läns Landsting, Heart Centre, Department of Cardiology.
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2000 (English)In: Atherosclerosis, ISSN 0021-9150, E-ISSN 1879-1484, Vol. 151, no 2, 501-508 p.Article in journal (Refereed) Published
Abstract [en]

Coronary heart disease mortality is four times higher in Lithuanian compared to Swedish middle-aged men. Using the same equipment (Acuson XP10 with 5 MHz linear transducer) and staff, we compared the amount of atherosclerosis in carotid and femoral arteries in 100 randomly sampled 50-year-old men in each of the cities Vilnius, Lithuania and Linköping, Sweden. Atherosclerotic plaques were more abundant in Vilnius men compared to Linköping men (53 versus 28% in the common carotid artery, 73 versus 37% in the common femoral artery, P<0.001 for both). Plaques were thicker and more extended in arteries of Vilnius men, and an ultrasound atherosclerosis score was higher in both carotid and femoral arteries (P<0.001 for all). More Vilnius men had a maximal intima-media thickness of the common femoral artery above 1 mm (P<0.005). Stiffness in the common carotid artery was higher in Vilnius men (P<0.001). In a linear regression model of the pooled material, after adjustment for city was made, smoking, systolic blood pressure, low density lipoprotein cholesterol and β-carotene (inversely) significantly contributed to a high total ultrasound score (r2=0.32). These findings show that the higher coronary mortality noted in Lithuanian men goes together with a higher prevalence of early peripheral atherosclerosis.

Place, publisher, year, edition, pages
2000. Vol. 151, no 2, 501-508 p.
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Medical and Health Sciences
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URN: urn:nbn:se:liu:diva-26002DOI: 10.1016/S0021-9150(99)00399-8Local ID: 10454OAI: oai:DiVA.org:liu-26002DiVA: diva2:246550
Available from: 2009-10-08 Created: 2009-10-08 Last updated: 2017-12-13

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Kristenson, MargaretaBergdahl, BjörnZiedén, BoOlsson, Anders

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Faculty of Health SciencesDepartment of health and environmentFörebygg.medClinical PhysiologyDepartment of Clinical PhysiologyCardiologyDepartment of CardiologyInternal MedicineGE: endomed
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Atherosclerosis
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