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Neonatal ventricular hypertrophy without cardiac malformations: A retrospective evaluation of 17 infants
Linköping University, Faculty of Health Sciences. Linköping University, Department of Molecular and Clinical Medicine, Pediatrics. Östergötlands Läns Landsting, Centre of Paediatrics and Gynecology and Obstetrics, Barn.
Linköping University, Faculty of Health Sciences. Linköping University, Department of Medicine and Care, Clinical Physiology. Östergötlands Läns Landsting, Heart Centre, Department of Clinical Physiology.
2001 (English)In: Prenatal and Neonatal Medicine, ISSN 1359-8635, Vol. 6, no 5, 318-322 p.Article in journal (Refereed) Published
Abstract [en]

Cardiac hypertrophy in the neonatal period is usually associated with other congenital defects of the circulatory system. Isolated ventricular hypertrophy can be difficult to evaluate and manage. We present 17 neonates with increased ventricular wall thickness without congenital malformations according to echocardiography during the neonatal period. The echocardiographic findings were defined as either concentric or predominantly septal hypertrophy. Doppler signs of ventricular outflow obstruction were found in six babies. The material consisted of preterm infants with steroid-treated bronchopulmonary dysplasia, metabolic disorders, perinatal infections, hypertrophic cardiomyopathy and babies with no identified underlying disorder. Six out of 17 patients died before the age of 8 months: all three babies with hypertrophic cardiomyopathy, one with toxoplasmosis and two out of four infants with steroid-treated bronchopulmonary dysplasia. It was not possible to predict the outcome from the initial clinical examination or from the first echocardiographic investigation. Ventricular wall thickness and outflow obstruction may undergo significant and rapid changes, and thus we recommend repeated echocardiographic examinations.

Place, publisher, year, edition, pages
2001. Vol. 6, no 5, 318-322 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-26062Local ID: 10521OAI: diva2:246610
Available from: 2009-10-08 Created: 2009-10-08 Last updated: 2011-01-13

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