Increased levels of nitric oxide metabolites in urine from leprosy patients in reversal reaction
1999 (English)In: Leprosy Review, ISSN 0305-7518, Vol. 70, no 1, 52-55 p.Article in journal (Refereed) Published
We measured the metabolites of NO [nitrite (NŌ 2) and nitrate (NŌ 3)] in urine from Ethiopian patients suffering from leprosy. The urinary level of NŌ 2/NŌ 3 in a group of healthy Ethiopians was 1020 ± 471 μM (n = 22). Leprosy patients in reversal reaction had significantly higher levels of NŌ 2/NŌ 3 (1817 ± 492 μM, P < 0.001, n = 12) than both the control group and leprosy patients who were not in reversal reaction (1079 ± 446 μM, n = 12). We conclude that the reversal reaction in leprosy is associated with increased urinary levels of nitric oxide metabolites.
Place, publisher, year, edition, pages
1999. Vol. 70, no 1, 52-55 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-26097PubMedID: 10438255Local ID: 10556OAI: oai:DiVA.org:liu-26097DiVA: diva2:246645