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Chronic symptoms are common in patients with neuroborreliosis - A questionnaire follow-up study
Linköping University, Faculty of Health Sciences. Linköping University, Department of Neuroscience and Locomotion. Östergötlands Läns Landsting, Local Health Care Services in Central Östergötland, Department of Neurology.
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2002 (English)In: Acta Neurologica Scandinavica, ISSN 0001-6314, Vol. 106, no 4, 205-208 p.Article in journal (Refereed) Published
Abstract [en]

Objectives - The existence of chronic neuroborreliosis is controversial. The aim of our study was to investigate the existence and kind of persistent symptoms in patients previously treated because of neurological symptoms as a result of neuroborreliosis. Material and methods - A total of 106 patients with neuroborreliosis, according to established criteria, and a control group of 123 patients with Borrelia induced erythema migrans diagnosed in a general practitioner office were studied. A questionnaire was sent to patients and controls concerning their health situation. Time from onset of neurological symptoms to the questionnaire sendout was 32 months (mean) for the patients with neuroborreliosis and 33 months (mean) for the controls. Results - Fifty per cent of the individuals in the patient group compared with 16% of the individuals in the control group showed persistent complaints after their Borrelia infection (P < 0.0001). The most significant differences between the groups were the presence of neuropsychiatric symptoms such as headache, attention problems, memory difficulties and depression. Paresthesia, pain and persistent facial palsy was also significantly more common in patients treated because of neuroborreliosis. Conclusion - Our study shows that persisting neurological symptoms are common after a neuroborreliosis infection. The pathological mechanisms that lay behind the development of chronic symptoms, however, are still uncertain.

Place, publisher, year, edition, pages
2002. Vol. 106, no 4, 205-208 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-26435DOI: 10.1034/j.1600-0404.2002.01358.xLocal ID: 10978OAI: diva2:246984
Available from: 2009-10-08 Created: 2009-10-08 Last updated: 2011-01-13

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Vrethem, MagnusErnerudh, JanForsberg, Pia
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Faculty of Health SciencesDepartment of Neuroscience and LocomotionDepartment of NeurologyClinical ImmunologyDepartment of Clinical Immunology and Transfusion MedicineInfectious DiseasesDepartment of Infectious Diseases in Östergötland
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Acta Neurologica Scandinavica
Medical and Health Sciences

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