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Prophylactic laser treatment in early age-related maculopathy: An 8-year follow-up in a randomized pilot study shows a reduced incidence of exudative complications
Linköping University, Faculty of Health Sciences. Linköping University, Department of Neuroscience and Locomotion, Ophthalmology. Östergötlands Läns Landsting, Reconstruction Centre, Department of Ophthalmology UHL/MH.
2003 (English)In: Acta Ophthalmologica Scandinavica, ISSN 1395-3907, Vol. 81, no 5, 449-454 p.Article in journal (Refereed) Published
Abstract [en]

Purpose: To study the effect of mild laser treatment on the incidence of exudative complications in patients with soft drusen maculopathy in a longterm perspective. Methods: In a prospective study, 38 patients with early age-related maculopathy and good visual acuity (VA) were randomized either to laser treatment using an argon green laser or to observation. At 8 years, 29 patients remained in the study, 16 in the control group and 13 in the treatment group. Results: During follow-up, mean VA decreased significantly in both groups, to 0.53 in the treatment group (p < 0.05) and to 0.25 in the control group (p < 0.001). At 8 years, 9/16 in the control group showed exudative complications, whereas only 2/13 in the treatment group developed such changes (p < 0.03). Conclusion: In this randomized pilot study, mild laser treatment of soft drusen maculopathy significantly reduced the rate of exudative complications in a longterm perspective. As the study is small, the results should be viewed with caution.

Place, publisher, year, edition, pages
2003. Vol. 81, no 5, 449-454 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-27753DOI: 10.1034/j.1600-0420.2003.00143.xLocal ID: 12498OAI: diva2:248305
Available from: 2009-10-08 Created: 2009-10-08 Last updated: 2011-01-13

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Frennesson, Christina
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Faculty of Health SciencesOphthalmologyDepartment of Ophthalmology UHL/MH
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