liu.seSearch for publications in DiVA
Change search
ReferencesLink to record
Permanent link

Direct link
Caudate nucleus dopamine D2 receptors in vascular dementia
Linköping University, Faculty of Health Sciences. Linköping University, Department of Neuroscience and Locomotion, Geriatrics. Östergötlands Läns Landsting, MC - Medicincentrum, Geriatrik-LAH.
2002 (English)In: Dementia and Geriatric Cognitive Disorders, ISSN 1420-8008, Vol. 14, no 1, 22-25 p.Article in journal (Refereed) Published
Abstract [en]

Caudate nucleus dopamine (DA) D2 receptors were studied in patients with vascular dementia (VaD) and in a control group using [3H]raclopride as a radioligand. There was no significant difference in the number of DA D2 receptors in the VaD group as compared with controls. The binding affinity was significantly lower in the VaD group. When the VaD group was subdivided into subjects with or without neuroleptic treatment, there were no differences in the numbers of receptors as compared with controls, and the significant differences in binding affinity remained for both VaD subgroups. The present results are discussed with reference to the previous finding of a reduced density of caudate nucleus DA uptake sites in the same VaD group and to results from studies on DA D2 receptors in Alzheimer's disease and Parkinson's disease. Copyright ⌐ 2002 S. Karger AG, Basel.

Place, publisher, year, edition, pages
2002. Vol. 14, no 1, 22-25 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-27876DOI: 10.1159/000058329Local ID: 12636OAI: diva2:248428
Available from: 2009-10-08 Created: 2009-10-08 Last updated: 2011-01-13

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Marcusson, Jan
By organisation
Faculty of Health SciencesGeriatricsGeriatrik-LAH
In the same journal
Dementia and Geriatric Cognitive Disorders
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 53 hits
ReferencesLink to record
Permanent link

Direct link