Does l-dopa treatment contribute to reduction in body weight in elderly patients with Parkinson's disease?
2005 (English)In: Acta Neurologica Scandinavica, ISSN 0001-6314, E-ISSN 1600-0404, Vol. 111, no 1, 12-20 p.Article in journal (Refereed) Published
Objective – Many patients with Parkinson's disease (PD) lose weight also early during the disease. The objective of the study was to investigate possible causative factors for this loss.
Materials and methods – In this report, 28 PD patients and 28 age- and sex-matched controls were repeatedly assessed with the focus on body weight, body fat mass, dysphagia, olfaction, physical activity, PD symptomatology and drug treatment.
Results – Weight loss was seen in PD patients both before and during l-dopa treatment.
Conclusion – The underlying disease could play a role, but our results also suggest that l-dopa per se could contribute to the weight loss.
Place, publisher, year, edition, pages
2005. Vol. 111, no 1, 12-20 p.
Parkinson's disease, L-dopa, weight loss, body fat mass
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-28547DOI: 10.1111/j.1600-0404.2004.00364.xLocal ID: 13700OAI: oai:DiVA.org:liu-28547DiVA: diva2:249357