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Superficial and deep sternal wound complications: Incidence, risk factors and mortality
IMT Linköpings universitet.
Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Medical Informatics.
Linköping University, Faculty of Health Sciences. Linköping University, Department of Medicine and Care, Thoracic Surgery. Östergötlands Läns Landsting, Heart Centre, Department of Thoracic and Vascular Surgery.
Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Medical Informatics.
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2001 (English)In: European Journal of Cardio-Thoracic Surgery, ISSN 1010-7940, Vol. 20, no 6, 1168-1175 p.Article in journal (Refereed) Published
Abstract [en]

Objectives: Sternal wound complications often have a late onset and are detected after patients are discharged from the hospital. In an effort to catch all sternal wound complications, different postdischarge surveillance methods have to be used. Together with this long-term follow-up an analysis of risk factors may help to identify patients at risk and can lead to more effective preventive and control measures. Methods: This retrospective study of 3008 adult patients who underwent consecutive cardiac surgery from January 1996 through September 1999 at Link÷ping University Hospital, Sweden, evaluated 42 potential risk factors by univariate analysis followed by backward stepwise multivariate logistic regression analysis. Results: Two-thirds of the 291 (9.7%) sternal wound complications that occurred were identified after discharge. Of the 291 patients, 47 (1.6%) had deep sternal infections, 50 (1.7%) had postoperative mediastinitis, and 194 (6.4%) had superficial sternal wound complications. Twenty-three variables were selected by univariate analysis (P<0.15) and included in a multivariate analysis where eight variables emerged as significant (P<0.05). Preoperative risk factors for deep sternal infections/mediastinitis were obesity, insulin-dependent diabetes, smoking, peripheral vascular disease, and high New York Heart Association score. An intraoperative risk factor was bilateral use of internal mammary arteries, and a postoperative risk factor was prolonged ventilator support. Risk factors for superficial sternal wound complications were obesity, and an age of <75 years. The 30 day mortality was 2.7% for patients without sternal wound complications and 2/291 (0.7%) for all patients with sternal wound complications, 0.5% for superficial sternal wound complications, and 1.0% for deep sternal infections/mediastinitis. The 1 year mortality rate was 4.8% for patients without sternal wound complications and 11/291 (3.8%) for patients with sternal wound complications, 2.1% for superficial sternal wound complications, and 7.2% for deep sternal infections/mediastinitis. Conclusions: The risk factors found in this study have been detected and reported in previous studies. The predictive ability was stronger though for deep sternal infections/mediastinitis (those needing surgical revisions) than for superficial sternal wound complications. Earlier recognition of sternal wound complications and aggressive treatment have probably contributed to the relatively low mortality rate seen in this study. Copyright ⌐ 2001 Elsevier Science B.V.

Place, publisher, year, edition, pages
2001. Vol. 20, no 6, 1168-1175 p.
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Medical and Health Sciences
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URN: urn:nbn:se:liu:diva-28806DOI: 10.1016/S1010-7940(01)00991-5Local ID: 13994OAI: oai:DiVA.org:liu-28806DiVA: diva2:249618
Available from: 2009-10-09 Created: 2009-10-09 Last updated: 2011-01-13

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Gill, HansGranfeldt, HansÅhlfeldt, HansRuthberg, Hans

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The Institute of TechnologyMedical InformaticsFaculty of Health SciencesThoracic SurgeryDepartment of Thoracic and Vascular SurgeryAnaesthesiologyDepartment of Intensive Care UHL
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European Journal of Cardio-Thoracic Surgery
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