Bedside monitoring of CBF with xenon-CT and a mobile scanner: A novel method in neurointensive care
2005 (English)In: British Journal of Neurosurgery, ISSN 0268-8697, Vol. 19, no 5, 395-401 p.Article in journal (Refereed) Published
Combining previously independently established techniques our objective was to develop and evaluate a method for bedside qualitative assessment of cerebral blood flow in neurointensive care (NICU) patients. The CT-protocol was optimized using phantoms and comparing a mobile CT-scanner (Tomoscan-M, Philips) with two stationary CT scanners. Thirty-two per cent xenon was delivered with standard equipment (Enhancer 3000). Mean cortical flow in volunteers was 48 ml/min/100 g, with the mean vascular territorial flow varying between 45 and 66 ml/min/100 g. The potential clinical usefulness was illustrated in three patients with vasospasm following subarachnoid haemorrhage. Our conclusion is that quantitative bedside measurements of CBF can be repeatedly performed in an easy and safe way in a standard NICU-setting, using xenon-inhalation and a mobile CT-scanner. The method is useful for the decision-making, and is a good example of how the quality of multi-modality monitoring in the NICU can be developed and further diversified. © The Neurosurgical Foundation.
Place, publisher, year, edition, pages
2005. Vol. 19, no 5, 395-401 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-30213DOI: 10.1080/02688690500389898Local ID: 15708OAI: oai:DiVA.org:liu-30213DiVA: diva2:251035