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Does consumption of ethanol distort measurements of exhaled nitric oxide?
Linköping University, Faculty of Health Sciences. Linköping University, Department of Biomedicine and Surgery, Division of clinical chemistry.
2005 (English)In: Respiratory Medicine, ISSN 0954-6111, E-ISSN 1532-3064, Vol. 99, no 2, 196-199 p.Article in journal (Refereed) Published
Abstract [en]

Background: Measuring FENO is a novel and non-invasive way to monitor airway inflammation (e.g. asthma). This clinical study was designed to investigate whether drinking ethanol might distort FENO measurements. Methods: Twenty healthy subjects drank 0.40 g ethanol/kg body weight in 15 min. Measurement of FENO started ∼ 30 min before drinking and at various times afterwards for 4 h post-dosing. Ethanol concentrations were determined in venous blood by gas chromatography and in end-exhaled breath by infra-red spectrometry. Results: The within subject standard deviation for determination of FENO was 1.3 ppb, corresponding to a CV of 7.7%. The mean change in FENO from pre-drinking levels during the 4 h testing was statistically significant (P

Place, publisher, year, edition, pages
2005. Vol. 99, no 2, 196-199 p.
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Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-31085DOI: 10.1016/j.rmed.2004.06.008Local ID: 16812OAI: oai:DiVA.org:liu-31085DiVA: diva2:251908
Available from: 2009-10-09 Created: 2009-10-09 Last updated: 2017-12-13

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Jones, A Wayne

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