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Phenotypic and genotypic characterization of prolyliminopeptidase-negative Neisseria gonorrhoeae isolates in Denmark.
H:S Hvidovre Hospital.
Örebro University Hospital.
Örebro University Hospital.
Danish Neisseria gonorrhoeae Reference Laboratory.
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2005 (English)In: European Journal of Clinical Microbiology and Infectious Diseases, ISSN 0934-9723, E-ISSN 1435-4373, Vol. 24, no 4, 280-283 p.Article in journal (Refereed) Published
Abstract [en]

In the study presented here 26 recent Danish clinical isolates of prolyliminopeptidase (PIP)-negative Neisseria gonorrhoeae were phenotypically and genotypically characterized to investigate whether one or more PIP-negative strains are circulating in the Danish community. The profiles of these isolates were compared with those of three isolates from a recent outbreak of PIP-negative N. gonorrhoeae infection in the UK. Twenty-five of the Danish isolates and all three UK isolates had similar antibiograms and were designated serovar IB-4. Genotypic characterization by pulsed-field gel electrophoresis, porB1b gene sequencing, and opa-typing revealed that these isolates were indistinguishable or closely related. The results indicate that at least one PIP-negative N. gonorrhoeae strain is currently circulating in the Danish community, and this strain is indistinguishable from the one that caused an outbreak in the UK.

Place, publisher, year, edition, pages
2005. Vol. 24, no 4, 280-283 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-32357DOI: 10.1007/s10096-005-1319-5Local ID: 18252OAI: diva2:253179
Available from: 2009-10-09 Created: 2009-10-09 Last updated: 2010-05-20

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Unemo, MagnusFredlund, Hans
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