IVF i Sverige - Fortsatt uppföljning av barn och mödrar
2006 (Swedish)In: Läkartidningen, ISSN 0023-7205, Vol. 103, no 32-33, 2301-2305 p.Article in journal (Refereed) Published
This paper summarises six recently published studies which evaluate Swedish in vitro fertilization from 1982 to 2003 and is a register study, based on national registers linked through personal identification numbers. Data were available for all 12186 mothers and their 16280 children. Comparisons were made with the total delivering population. The number of children born after IVF increases steadily and amounts to 3% presently. The number of twins has decreased considerably. Some increased risks persist after IVF, a slightly higher perinatal death rate and an increased risk for congenital malformations. There were no differences between conventional IVF and ICSI. The risk for cancer was not increased with one possible exception, histiocytosis. Morbidity during childhood measured as hospital admissions, was increased due to more preterm births and multiple births in the IVF group. IVF mothers were older and smoked less than other mothers. Their medical drug use differed from that of other pregnant women. In general they had a decreased cancer risk, but probably an increased risk for ovarian cancer. Maternal mortality was not increased. Several obstetric complications were more common in IVF mothers: ovarial torsion, preeclampsia, premature rupture of membranes, bleeding at delivery and placental abruption. The deliveries were more often induced, and the frequency of caesarean section was increased.
Place, publisher, year, edition, pages
2006. Vol. 103, no 32-33, 2301-2305 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-34898Local ID: 23890OAI: oai:DiVA.org:liu-34898DiVA: diva2:255746