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Recommendation for measuring and reporting chloride by ISEs in undiluted serum, plasma or blood
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2006 (English)In: Clinical Chemistry and Laboratory Medicine, ISSN 1434-6621, Vol. 44, no 3, 346-352 p.Article in journal (Refereed) Published
Abstract [en]

The proposed recommendation for measuring and reporting chloride in undiluted plasma† or blood by ion-selective electrodes (ISEs) will provide results that are identical to chloride concentrations measured by coulometry for standardized normal plasma or blood samples. It is applicable to all current ISEs dedicated to chloride measurement in undiluted samples that meet the requirements. However, in samples with reduced water concentration, results by coulometry are lower than by ion-selective electrode due to volume displacement. The quantity measured by this standardized ISE procedure is called the ionized chloride concentration. It may be clinically more relevant than the chloride concentration as determined by coulometry, photometry or by ISE after dilution of the sample. © 2006 by Walter de Gruyter.

Place, publisher, year, edition, pages
2006. Vol. 44, no 3, 346-352 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-36098DOI: 10.1515/CCLM.2006.060Local ID: 29869OAI: diva2:256946
Available from: 2009-10-10 Created: 2009-10-10 Last updated: 2011-01-11

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Larsson, Lasse
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Faculty of Health SciencesDivision of clinical chemistryDepartment of Clinical Chemistry
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