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PLC analysis of methylxanthines and selected drugs in urine samples
Linköping University, Faculty of Health Sciences. Linköping University, Department of Medicine and Care, Physiology. Östergötlands Läns Landsting, Heart Centre, Department of Clinical Physiology.
2006 (English)In: Chemia Analityczna, ISSN 0009-2223, Vol. 51, no 5, 751-760 p.Article in journal (Refereed) Published
Abstract [en]

A HPLC system for separation and determination of methylxanthines and selected drugs has been developed. Teophylline, 1-methylxanthine, 3-methylxanthine, 1,3-dimethyluric acid, caffeine, paracetamol, furosemide, dexamethasone, prednisolone, cefazolin and imipenem have been determined. A RP-18e column with a RP-18 pre-column and a DAD detector were used. Gradient elution with 0.05% TFA aqueous solution with acetononitrile at the flow rate of 0.8 mL min-1 was applied. The developed system was used to determine the examined compounds in urine samples.

Place, publisher, year, edition, pages
2006. Vol. 51, no 5, 751-760 p.
Keyword [en]
methylxanthines, drugs, HPLC, urine
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-37810Local ID: 38825OAI: diva2:258659
Available from: 2009-10-10 Created: 2009-10-10 Last updated: 2011-01-11

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