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Multiple sclerosis with and without CSF bands: Clinically indistinguishable but immunogenetically distinct
Linköping University, Faculty of Health Sciences. Linköping University, Department of Neuroscience and Locomotion, Neurology. Östergötlands Läns Landsting, Local Health Care Services in Central Östergötland, Department of Neurology.
2006 (English)In: Neurology, ISSN 0028-3878, Vol. 67, no 6, 1062-1064 p.Article in journal (Refereed) Published
Abstract [en]

We sought to determine whether Swedish patients with multiple sclerosis (MS) with and without oligoclonal bands (OCBs) in the CSF constitute distinct subpopulations, clinically and immunogenetically. Our findings indicate that OCB-negative MS shares the same clinical features as OCB-positive MS regarding female predominance, age at onset, proportion of primary progressive cases, rate of MRI positivity, and disease severity. Our HLA-DRB1 genotyping results suggest, however, that OCB-positive and OCB-negative MS are immunogenetically distinct. Copyright © 2006 by AAN Enterprises, Inc.

Place, publisher, year, edition, pages
2006. Vol. 67, no 6, 1062-1064 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-37826DOI: 10.1212/01.wnl.0000237343.93389.35Local ID: 39326OAI: diva2:258675
Available from: 2009-10-10 Created: 2009-10-10 Last updated: 2011-01-11

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Landtblom, Anne-Marie
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Faculty of Health SciencesNeurologyDepartment of Neurology
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