Multiple sclerosis with and without CSF bands: Clinically indistinguishable but immunogenetically distinct
2006 (English)In: Neurology, ISSN 0028-3878, Vol. 67, no 6, 1062-1064 p.Article in journal (Refereed) Published
We sought to determine whether Swedish patients with multiple sclerosis (MS) with and without oligoclonal bands (OCBs) in the CSF constitute distinct subpopulations, clinically and immunogenetically. Our findings indicate that OCB-negative MS shares the same clinical features as OCB-positive MS regarding female predominance, age at onset, proportion of primary progressive cases, rate of MRI positivity, and disease severity. Our HLA-DRB1 genotyping results suggest, however, that OCB-positive and OCB-negative MS are immunogenetically distinct. Copyright © 2006 by AAN Enterprises, Inc.
Place, publisher, year, edition, pages
2006. Vol. 67, no 6, 1062-1064 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-37826DOI: 10.1212/01.wnl.0000237343.93389.35Local ID: 39326OAI: oai:DiVA.org:liu-37826DiVA: diva2:258675