Total internal reflection ellipsometry: ultrahigh sensitivity for protein adsorption on metal surfaces
2007 (English)In: Optics Letters, ISSN 0146-9592, E-ISSN 1539-4794, Vol. 32, no 10, 1308-1310 p.Article in journal (Refereed) Published
Total internal reflection ellipsometry (TIRE) is used to study adsorption of human serum albumin and fibrinogen on thin gold films. TIRE shows very high sensitivity for protein monolayers adsorbed on metal surfaces when surface plasmon resonance effects are utilized. The measured data, expressed in ellipsometric angles ψ and Δ are of several orders of magnitude larger in comparison with those from similar experiments performed with traditional ellipsometry. TIRE in spectral mode opens a new path for precise studies of organic layers adsorbed on metal surfaces, with a potential for resolving the adsorbed layer microstructure.
Place, publisher, year, edition, pages
2007. Vol. 32, no 10, 1308-1310 p.
IdentifiersURN: urn:nbn:se:liu:diva-39198DOI: 10.1364/OL.32.001308Local ID: 47150OAI: oai:DiVA.org:liu-39198DiVA: diva2:260047