ZnO nanorods as an intracellular sensor for pH measurements
2007 (English)In: Journal of Applied Physics, ISSN 0021-8979, Vol. 102, no 8Article in journal (Refereed) Published
ZnO nanorods with 80 nm diameter and 700 nm length and grown on the tip of a borosilicate glass capillary (0.7 μm in diameter) were used to create a highly sensitive pH sensor for monitoring in vivo biological process within single cells. The ZnO nanorods, functionalized by proton H3 O+ and hydroxyl O H- groups, exhibit a pH -dependent electrochemical potential difference versus a AgAgCl microelectrode. The potential difference was linear over a large dynamic range (4-11), which could be understood in terms of the change in surface charge during protonation and deprotonation. These nanoelectrode devices have the ability to enable analytical measurements in single living cells and have the capability to sense individual chemical species in specific locations within a cell. © 2007 American Institute of Physics.
Place, publisher, year, edition, pages
2007. Vol. 102, no 8
Engineering and Technology
IdentifiersURN: urn:nbn:se:liu:diva-41077DOI: 10.1063/1.2798582Local ID: 55048OAI: oai:DiVA.org:liu-41077DiVA: diva2:261927