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ZnO nanorods as an intracellular sensor for pH measurements
Linköping University, The Institute of Technology. Linköping University, Department of Science and Technology.ORCID iD: 0000-0001-6235-7038
Linköping University, Faculty of Health Sciences. Linköping University, Department of Biomedicine and Surgery, Division of cell biology.
Linköping University, Faculty of Health Sciences. Linköping University, Department of Biomedicine and Surgery, Division of cell biology.
2007 (English)In: Journal of Applied Physics, ISSN 0021-8979, E-ISSN 1089-7550, Vol. 102, no 8Article in journal (Refereed) Published
Abstract [en]

ZnO nanorods with 80 nm diameter and 700 nm length and grown on the tip of a borosilicate glass capillary (0.7 μm in diameter) were used to create a highly sensitive pH sensor for monitoring in vivo biological process within single cells. The ZnO nanorods, functionalized by proton H3 O+ and hydroxyl O H- groups, exhibit a pH -dependent electrochemical potential difference versus a AgAgCl microelectrode. The potential difference was linear over a large dynamic range (4-11), which could be understood in terms of the change in surface charge during protonation and deprotonation. These nanoelectrode devices have the ability to enable analytical measurements in single living cells and have the capability to sense individual chemical species in specific locations within a cell. © 2007 American Institute of Physics.

Place, publisher, year, edition, pages
2007. Vol. 102, no 8
National Category
Engineering and Technology
Identifiers
URN: urn:nbn:se:liu:diva-41077DOI: 10.1063/1.2798582Local ID: 55048OAI: oai:DiVA.org:liu-41077DiVA: diva2:261927
Available from: 2009-10-10 Created: 2009-10-10 Last updated: 2017-12-13

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Willander, MagnusÖst, AnitaStrålfors, Peter

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The Institute of TechnologyDepartment of Science and TechnologyFaculty of Health SciencesDivision of cell biology
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