liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Can selective serotonin inhibitor drugs in elderly patients in nursing homes be reduced?
Unit of Research and Development in Primary Care, Jönköping, Sweden.
Department of Research and Development, National Corporation of Swedish Pharmacies.
Department of Research and Development, National Corporation of Swedish Pharmacies.
Unit of Research and Development in Primary Care, Jönköping, Sweden and Department of Nursing Science, School of Health Sciences, Jönköping, Sweden.
Show others and affiliations
2007 (English)In: Scandinavian Journal of Primary Health Care, ISSN 0281-3432, E-ISSN 1502-7724, Vol. 25, no 1, 3-8 p.Article in journal (Refereed) Published
Abstract [en]

Objective. To investigate whether treatment with selective serotonin reuptake inhibitors (SSRIs) could be withdrawn for elderly residents who had been on treatment for at least one year and to evaluate a method for systematic drug review.

Design. Open, prospective, interventional study.

Setting. Four counties in Sweden. Subjects. Elderly residents at 19 nursing homes, with ongoing treatment with SSRIs for more than one year.

Main outcome measures. Clinical evaluation, registration of drugs used and rating with Montgomery–Åsberg Depression Rating Scale (MADRS). A semi-structured telephone interview with 15 participating physicians and 19 nurses.

Results. About one-third of all 822 residents in the nursing homes had ongoing antidepressant treatment, predominantly with SSRIs; 75% of them had been treated with SSRIs for at least one year and 119 (60%) of these were considered eligible for the study. The intervention was judged successful in 52% of these residents of whom 88% had a MADRS rating of less than 20 points. The GPs and the nurses experienced the method as practicable.

Conclusions. Withdrawal of SSRI treatment was successful in the majority of cases. The MADRS may be a valuable addition to clinical evaluation when deciding whether to end or continue SSRI treatment.

Place, publisher, year, edition, pages
2007. Vol. 25, no 1, 3-8 p.
Keyword [en]
Family practice, nursing homes, SSRI drugs, systematic drug review, withdrawal
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-41432DOI: 10.1080/02813430600958427Local ID: 56453OAI: oai:DiVA.org:liu-41432DiVA: diva2:262284
Available from: 2009-10-10 Created: 2009-10-10 Last updated: 2017-12-13Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Authority records BETA

Lindström, KjellMölstad, Sigvard

Search in DiVA

By author/editor
Lindström, KjellMölstad, Sigvard
By organisation
General PracticeFaculty of Health Sciences
In the same journal
Scandinavian Journal of Primary Health Care
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 49 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf