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Risk factors for local recurrence in patients with pTa/pT1 urinary bladder cancer
Linköping University, Faculty of Health Sciences. Linköping University, Department of Clinical and Experimental Medicine.
Linköping University, Faculty of Health Sciences. Linköping University, Department of Clinical and Experimental Medicine, Surgery . Östergötlands Läns Landsting, Centre of Surgery and Oncology, Department of Urology in Östergötland.
Linköping University, Faculty of Health Sciences. Linköping University, Department of Clinical and Experimental Medicine, Oncology . Östergötlands Läns Landsting, Centre of Surgery and Oncology, Department of Oncology UHL.
Linköping University, Faculty of Health Sciences. Linköping University, Department of Clinical and Experimental Medicine, Surgery . Östergötlands Läns Landsting, Centre of Surgery and Oncology, Department of Urology in Östergötland.
2008 (English)In: Scandinavian Journal of Urology and Nephrology, ISSN 0036-5599, Vol. 42, no 5, 417-421 p.Article in journal (Refereed) Published
Abstract [en]

Objective. This study evaluated risk factors for local tumour recurrence, defined as recurrence at the same location in the bladder within 18 months after primary resection in patients with newly diagnosed pTa or pT1 bladder cancer. Patients and methods. The study included 472 patients with newly diagnosed pTa/T1 bladder cancer between 1992 and 2001. The patients were followed prospectively in accordance with a control programme and possible risk factors for tumour recurrence were registered. Results. Local tumour recurrence was observed in 164 (35%) patients, another 117 (25%) patients had recurrence at other locations in the bladder (non-local recurrence) and 191 (40%) had no recurrence at all. Tumour size and multiple tumours were significantly associated with a higher risk for developing local recurrence as opposed to non-local recurrence. Tumour category was of borderline statistical significance. Gender and tumour grade were not found to be risk factors for developing local recurrence. Conclusion. Tumour size and multiplicity are risk factors for development of recurrence at the same location in the bladder as the primary tumour. Local tumour recurrence may be a result of non-radical primary transurethral resection. One may consider recommending standard re-resection within 6-8 weeks in patients with tumours >3 cm or those with multiple primary tumours. © 2008 Informa UK Ltd. (Informa Healthcare, Taylor & Francis AS).

Place, publisher, year, edition, pages
2008. Vol. 42, no 5, 417-421 p.
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-43347DOI: 10.1080/00365590802016302Local ID: 73621OAI: oai:DiVA.org:liu-43347DiVA: diva2:264206
Available from: 2009-10-10 Created: 2009-10-10 Last updated: 2011-01-10

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Jancke, GeorgDamm, OleRosell, JohanJahnson, Staffan

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Faculty of Health SciencesDepartment of Clinical and Experimental MedicineSurgery Department of Urology in ÖstergötlandOncology Department of Oncology UHL
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Scandinavian Journal of Urology and Nephrology
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