Subject Specific Wall Shear Stress in the Human Thoracic Aorta
2006 (English)In: WSEAS Transaction on biology and biomedicine, ISSN 1109-9518, Vol. 10, no 3, 609-614 p.Article in journal (Refereed) Published
Numerous studies have shown a correlation between Wall Shear Stress (WSS) and atherosclerosis, but few have evaluated the reliability of estimation methods and measures used to assessWSS, which is the subject of this work. A subject specific vessel model of the aortic arch and thoracic aorta is created fromMRI images and used for CFD simulations with MRI velocity measurements as inlet boundary condition. WSS is computed from the simulation results. Aortic WSS shows significant spatial as well as temporal variation during a cardiac cycle, which makes circumferential values very uninformative, and approximate estimates using Hagen-Poiseuille fails predict the averageWSS. Highly asymmetric flow, especially in the arch, causes the spatial WSS variations.
Place, publisher, year, edition, pages
2006. Vol. 10, no 3, 609-614 p.
Wall shear stress, CFD, Aorta, Circumferential average values, Asymmetric flow
Engineering and Technology
IdentifiersURN: urn:nbn:se:liu:diva-43727Local ID: 74619OAI: oai:DiVA.org:liu-43727DiVA: diva2:264587