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Online Laser Doppler Measurements of Myocardial Perfusion
Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Instrumentation.
Linköping University, Faculty of Health Sciences. Linköping University, Department of Medical and Health Sciences, Thoracic Surgery. Östergötlands Läns Landsting, Heart Centre, Department of Thoracic and Vascular Surgery.
Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Instrumentation.
2008 (English)In: IFMBE Proceedings 22,2008, Springer Berlin Heidelberg , 2008, 1718-1721 p.Conference paper (Refereed)
Abstract [en]

Laser Doppler perfusion monitoring is a suitable method for microvascular blood perfusion measurements. When used on a moving tissue or organ, the Doppler signal arising from the moving blood cells may be distorted. ECG triggering of the laser Doppler signal can be used for reducing the influence from movements during measurements on the beating heart. The aim of this study was to determine the most appropriate triggering intervals during the cardiac cycle for online measurements. Recordings from thirteen coronary artery bypass graft (CABG) patients were included in the study. During surgery, the fibre-optic probe was passed through the chest wall and sutured to the left anterior ventricular wall with the probe tip inserted 3–5 mm into the myocardium. After the patient arrived at the intensive care unit a second measurement was initiated and lasted for about two hours. Before the probe was removed a third measurement was performed for about 5 minutes the following morning. A total of 97 data sequences were analysed and the intervals of low and stable perfusion signal were compared to the positions of the T and P peaks in the ECG.

It was found that the most appropriate time intervals were in late systole at the T peak [−3, 9] ms and just before the P peak [−28, -10] ms in late diastole. However, the position of these intervals may vary between individuals, because of e.g., abnormal cardiac motion. With the use of the appropriate interval online measurement of the myocardial perfusion on a beating heart appears possible.

Place, publisher, year, edition, pages
Springer Berlin Heidelberg , 2008. 1718-1721 p.
, IFMBE Proceedings, ISSN 1680-0737 ; 22
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-44433DOI: 10.1007/978-3-540-89208-3_409Local ID: 76617ISBN: 978-3-540-89207-6 (print)ISBN: 978-3-540-89208-3 (online)OAI: diva2:265295
4th European Conference of the International Federation for Medical and Biological Engineering, ECIFMBE
Available from: 2009-10-10 Created: 2009-10-10 Last updated: 2015-06-10

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Fors, CarinaAhn, Henrik CasimirWårdell, Karin
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The Institute of TechnologyBiomedical InstrumentationFaculty of Health SciencesThoracic SurgeryDepartment of Thoracic and Vascular Surgery
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