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Recent developments in the monitoring, modeling and control of biological production systems
Linköping University, The Institute of Technology. Linköping University, Department of Physics, Chemistry and Biology, Biotechnology .
2004 (English)In: Bioprocess and biosystems engineering (Print), ISSN 1615-7591, Vol. 26, no 6, 347-351 p.Article, review/survey (Refereed) Published
Abstract [en]

Current trends in the development of methods for monitoring, modeling and controlling biological production systems are reviewed from a bioengineering perspective. The ability to measure intracellular conditions in bioprocesses using genomics and other bioinformatics tools is addressed. Devices provided via micromachining techniques and new real-time optical technology are other novel methods that may facilitate biosystem engineering. Mathematical modeling of data obtained from bioinformatics or real-time monitoring methods are necessary in order to handle the dense flows of data that are generated. Furthermore, control methods must be able to cope with these data flows in efficient ways that can be implemented in plant-wide computer communication systems.

Place, publisher, year, edition, pages
2004. Vol. 26, no 6, 347-351 p.
Keyword [en]
genomics and proteomics, chemometrics, multivariate process control, in situ optical sensors, miniaturized devices, control models
National Category
Engineering and Technology
URN: urn:nbn:se:liu:diva-46149DOI: 10.1007/s0449-004-0383-zOAI: diva2:267045
Available from: 2009-10-11 Created: 2009-10-11 Last updated: 2011-01-12

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Mandenius, Carl-Fredrik
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