Factors of importance for weight loss in elderly patients with Parkinson's disease
2004 (English)In: Acta Neurologica Scandinavica, ISSN 0001-6314, E-ISSN 1600-0404, Vol. 110, no 3, 180-187 p.Article in journal (Refereed) Published
Objective – Weight loss is reported frequently in patients with Parkinson's disease (PD). The objective of this study was to find the underlying factors of this phenomenon.
Participants and methods – Twenty-six l-dopa-treated patients with PD and 26 age- and sex-matched healthy controls were assessed twice within a 1-year interval. Body weight, body fat mass, resting energy expenditure, physical activity, energy intake, thyroid hormones and cognitive function were investigated.
Results – Nineteen (73%) of the PD patients lost body weight, although energy intake and the time for rest increased. Weight loss was most marked in patients with more severe PD symptoms and in whom cognitive function had decreased. Multiple regression analyses showed that determinants for weight loss were female gender, age and low physical activity.
Conclusion – Weight loss was common in PD patients, in spite of the increased energy intake and was most obvious in patients with increased PD symptoms and decreased cognitive function.
Place, publisher, year, edition, pages
2004. Vol. 110, no 3, 180-187 p.
Parkinson's disease, weight loss, body fat mass, energy expenditure, energy intake, thyroid hormones, physical activity, cognitive function
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-46206DOI: 10.1111/j.1600-0404.2004.00307.xOAI: oai:DiVA.org:liu-46206DiVA: diva2:267102