liu.seSearch for publications in DiVA
Change search
ReferencesLink to record
Permanent link

Direct link
Simultaneous analysis of ?-hydroxybutyric acid, ?-butyrolactone, and 1,4-butanediol by micellar electrokinetic chromatography
Forensic Science Unit, University of Strathclyde, 204 George Street, Glasgow G1 1XW, United Kingdom.
2002 (English)In: Forensic Science International, ISSN 0379-0738, Vol. 125, no 2-3, 113-119 p.Article in journal (Refereed) Published
Abstract [en]

A micellar electrokinetic chromatography (MEKC) method was optimised for simultaneous analysis of ?-hydroxybutyric acid (GHB), ?-butyrolactone (GBL), and 1,4-butanediol (BD). Best conditions for separation and baseline stability were achieved using a carrier electrolyte comprising 30.0mM sodium barbital and 150.0mM sodium dodecyl sulphate (SDS) at pH 10.2. Calibration functions were linear, giving correlation coefficients (r2) >0.998 for the three target compounds. Limits of detection (LOD) defined as three times the noise, were 5.1mg/l, 0.34 and 0.25g/l for GHB, GBL and BD, respectively. The repeatability of migration times and peak areas, expressed as the R.S.D. (n=9) was better than 0.41 and 3.05%, respectively. Some casework samples were analysed using the optimised conditions. Copyright © 2002 Elsevier Science Ireland Ltd.

Place, publisher, year, edition, pages
2002. Vol. 125, no 2-3, 113-119 p.
Keyword [en]
?-Butyrolactone, ?-Hydroxybutyric acid, 1, 4-Butanediol, Capillary electrophoresis, Micellar electrokinetic chromatography
National Category
Natural Sciences
URN: urn:nbn:se:liu:diva-47089DOI: 10.1016/S0379-0738(02)00006-3OAI: diva2:267985
Available from: 2009-10-11 Created: 2009-10-11 Last updated: 2011-01-13

Open Access in DiVA

No full text

Other links

Publisher's full text
In the same journal
Forensic Science International
Natural Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 44 hits
ReferencesLink to record
Permanent link

Direct link