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Cost-effectiveness of lumbar fusion and nonsurgical treatment for chronic low back pain in the Swedish lumbar spine study: A multicenter, randomized, controlled trial from the Swedish Lumbar Spine Study Group
Department of Orthopedic Surgery, Falun Hospital, Falun, Sweden. (The Swedish Lumbar Spine Study Group)
Department of Orthopedic Surgery, Sahlgrenska University Hospital, Göteborg, Sweden. (The Swedish Lumbar Spine Study Group)
Linköping University, Department of Medical and Health Sciences, Health Technology Assessment. Linköping University, Faculty of Health Sciences.
Department of Orthopedic Surgery, Sahlgrenska University Hospital, Göteborg, Sweden. (The Swedish Lumbar Spine Study Group)
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2004 (English)In: Spine, ISSN 0362-2436, E-ISSN 1528-1159, Vol. 29, no 4, 421-434 p.Article in journal (Refereed) Published
Abstract [en]

Study Design. A cost-effectiveness study was performed from the societal and health care perspectives. Objective. To evaluate the costs-effectiveness of lumbar fusion for chronic low back pain (CLBP) during a 2-year follow-up. Summary of Background Data. A full economic evaluation comparing costs related to treatment effects in patients with CLBP is lacking. Patients and Methods. A total of 284 of 294 patients with CLBP for at least 2 years were randomized to either lumbar fusion or a nonsurgical control group. Costs for the health care sector ( direct costs), and costs associated with production losses ( indirect costs) were calculated. Societal total costs were identified as the sum of direct and indirect costs. Treatment effects were measured using patient global assessment of improvement, back pain ( VAS), functional disability (Owestry), and return to work. Results. The societal total cost per patient ( standard deviations) in the surgical group was significantly higher than in the nonsurgical group: Swedish kroner (SEK) 704,000 ( 254,000) vs. SEK 636,000 ( 208,000). The cost per patient for the health care sector was significantly higher for the surgical group, SEK 123,000 ( 60,100) vs. 65,200 ( 38,400) for the control group. All treatment effects were significantly better after surgery. The incremental cost-effectiveness ratio ( ICER), illustrating the extra cost per extra effect unit gained by using fusion instead of nonsurgical treatment, were for improvement: SEK 2,600 ( 600 - 5,900), for back pain: SEK 5,200 ( 1,100 - 11,500), for Oswestry: SEK 11,300 ( 1,200 - 48,000), and for return to work: SEK 4,100 ( 100 21,400). Conclusion. For both the society and the health care sectors, the 2-year costs for lumbar fusion was significantly higher compared with nonsurgical treatment but all treatment effects were significantly in favor of surgery. The probability of lumbar fusion being cost-effective increased with the value put on extra effect units gained by using surgery.

Place, publisher, year, edition, pages
Lippincott Williams & Wilkins, 2004. Vol. 29, no 4, 421-434 p.
Keyword [en]
chronic low back pain, degenerative disc disease, lumbar spinal fusion, RCT, prospective randomized controlled study, cost-effectiveness analysis, sensitivity analysis, societal perspective, health care perspective
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URN: urn:nbn:se:liu:diva-48406DOI: 10.1097/01.BRS.0000102681.61791.12ISI: 000220041000012PubMedID: 15094539OAI: diva2:269302
Available from: 2009-10-11 Created: 2009-10-11 Last updated: 2015-03-20Bibliographically approved

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Jonsson, DickReigo, TomasTropp, Hans
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Health Technology AssessmentFaculty of Health SciencesOrthopaedics and Sports MedicineDepartment of Orthopaedics Norrköping
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