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DNA and cell cycle analysis as prognostic indicators in breast tumors revisited
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2001 (English)In: Clinics in Laboratory Medicine, ISSN 0272-2712, Vol. 21, no 4, 875-+ p.Article in journal (Refereed) Published
Abstract [en]

Both DNA ploidy and S-phase ploidy are promising prognostic factors for node-negative breast cancer patients. Based largely on the analysis of one large study, much of the reported problems with these factors have been caused by some unappreciated complexities in categorizing DNA ploidy into low- and high-risk groups and the lack of some necessary adjustments to eliminate unwanted correlations between DNA S-phase and ploidy. When both DNA ploidy and S-phase are compensated properly, they become independent prognostic markers, forming a powerful prognostic model.

Place, publisher, year, edition, pages
2001. Vol. 21, no 4, 875-+ p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-49041OAI: diva2:269937
Available from: 2009-10-11 Created: 2009-10-11 Last updated: 2013-01-16

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Stål, Olle
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OncologyFaculty of Health Sciences
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