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DNA and cell cycle analysis as prognostic indicators in breast tumors revisited
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2001 (English)In: Clinics in Laboratory Medicine, ISSN 0272-2712, E-ISSN 1557-9832, Vol. 21, no 4, 875-+ p.Article in journal (Refereed) Published
Abstract [en]

Both DNA ploidy and S-phase ploidy are promising prognostic factors for node-negative breast cancer patients. Based largely on the analysis of one large study, much of the reported problems with these factors have been caused by some unappreciated complexities in categorizing DNA ploidy into low- and high-risk groups and the lack of some necessary adjustments to eliminate unwanted correlations between DNA S-phase and ploidy. When both DNA ploidy and S-phase are compensated properly, they become independent prognostic markers, forming a powerful prognostic model.

Place, publisher, year, edition, pages
2001. Vol. 21, no 4, 875-+ p.
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Medical and Health Sciences
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URN: urn:nbn:se:liu:diva-49041OAI: oai:DiVA.org:liu-49041DiVA: diva2:269937
Available from: 2009-10-11 Created: 2009-10-11 Last updated: 2017-12-12

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Stål, Olle

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