DNA and cell cycle analysis as prognostic indicators in breast tumors revisited
2001 (English)In: Clinics in Laboratory Medicine, ISSN 0272-2712, Vol. 21, no 4, 875-+ p.Article in journal (Refereed) Published
Both DNA ploidy and S-phase ploidy are promising prognostic factors for node-negative breast cancer patients. Based largely on the analysis of one large study, much of the reported problems with these factors have been caused by some unappreciated complexities in categorizing DNA ploidy into low- and high-risk groups and the lack of some necessary adjustments to eliminate unwanted correlations between DNA S-phase and ploidy. When both DNA ploidy and S-phase are compensated properly, they become independent prognostic markers, forming a powerful prognostic model.
Place, publisher, year, edition, pages
2001. Vol. 21, no 4, 875-+ p.
National CategoryMedical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-49041OAI: oai:DiVA.org:liu-49041DiVA: diva2:269937