liu.seSearch for publications in DiVA
Change search
ReferencesLink to record
Permanent link

Direct link
On the formation of fibrous capsule and fluid space around machined and porous blood plasma clot coated titanium
Linkoping Univ, Dept Phys & Measurement Technol, Appl Phys Lab, SE-58183 Linkoping, Sweden Univ Gothenburg, Inst Anat & Cell Biol, SE-40530 Gothenburg, Sweden.
Linköping University, The Institute of Technology. Linköping University, Department of Physics, Chemistry and Biology, Applied Physics .
Show others and affiliations
2001 (English)In: Journal of materials science. Materials in medicine, ISSN 0957-4530, Vol. 12, no 10-12, 1019-1024 p.Article in journal (Refereed) Published
Abstract [en]

Machined and machined submicron porous titanium, with and without a thin blood plasma coating (100 nm), were implanted for 7 or 28 days in subcutaneous pockets on the back of the rat. After explantation the specimens were analyzed by light microscopy with respect to thickness of the fibrous capsule, the fluid space width between implants and fibrous capsule, and formation of blood vessels. The results at 7 days indicate a thinnest fluid space for the plasma clot coated porous titanium surface, and the spaces vanished at the light microscopic level after 28 days outside all the analyzed surfaces. The thickness of the fibrous capsule increased outside the different surfaces at 7-28 days, and in this respect no significant differences were observed between the different surfaces at any time. Analysis of neovascularization showed that the number of vessels and proportion of vessels in the fibrous capsule increased with time at all surfaces, except machined Ti where the number instead decreased from 7 to 28 days. The average distance between the blood vessels and the fluid space increased with time for all types of surfaces. The results in the present study indicate that the healing process around titanium can be modulated by porosity and thin pre-prepared plasma coatings. (C) Kluwer Academic Publishers.

Place, publisher, year, edition, pages
2001. Vol. 12, no 10-12, 1019-1024 p.
National Category
Engineering and Technology
URN: urn:nbn:se:liu:diva-49063OAI: diva2:269959
Available from: 2009-10-11 Created: 2009-10-11 Last updated: 2011-01-13

Open Access in DiVA

No full text

Search in DiVA

By author/editor
Tengvall, Pentti
By organisation
The Institute of TechnologyApplied Physics
In the same journal
Journal of materials science. Materials in medicine
Engineering and Technology

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Total: 21 hits
ReferencesLink to record
Permanent link

Direct link