liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
The effect of pH changes on the crystallization of calcium salts in solutions with an ion composition corresponding to that in the distal tubule
Vastervik Hosp, Dept Surg, S-59381 Vastervik, Sweden Linkoping Univ Hosp, Fac Hlth Sci, Dept Biomed & Surg, Div Urol, S-58185 Linkoping, Sweden Linkoping Univ Hosp, Fac Hlth Sci, Clin Res Ctr, S-58185 Linkoping, Sweden.
Linköping University, Faculty of Arts and Sciences. Linköping University, Department of health and environment.
Vastervik Hosp, Dept Surg, S-59381 Vastervik, Sweden Linkoping Univ Hosp, Fac Hlth Sci, Dept Biomed & Surg, Div Urol, S-58185 Linkoping, Sweden Linkoping Univ Hosp, Fac Hlth Sci, Clin Res Ctr, S-58185 Linkoping, Sweden.
1999 (English)In: Urological research, ISSN 0300-5623, E-ISSN 1434-0879, Vol. 27, no 6, 409-416 p.Article in journal (Refereed) Published
Abstract [en]

The effect of pH changes on the crystallization in solutions with an ion composition assumed to correspond to that of urine in the distal part of the distal tubule was examined by recording the number and volume of crystals with a Coulter Multisizer and by studying the crystal morphology with scanning electron microscopy at different degrees of volume reduction. The experiments were carried out with 100 ml samples at different starting pH values without and with 20% of dialysed urine (dU). The number of crystals increased in response to the volume reduction. In solutions without dU, 100 or more crystals with a diameter in the range 2.4-45 mu m were observed already at a volume reduction of 40% when the initial pH was 7.28. For solutions with a pH of 5.80 and 6.45 the corresponding values were 60% and 80%, respectively. In the presence of dU, an appearance of crystals was recorded at volume reductions of less than 20%. In solutions with an initial pH of 5.80 and 6.45, the crystal number was greater with dU than without, such a difference was not recorded at pH 7.28. In samples containing dU, the mean crystal volume (MCV) varied very little when the sample volume was reduced. The same was found in solutions without dU when the initial pH was 5.80 and 7.28, whereas the MCV was greater in the samples with pH 6.45. Scanning electron microscopy of solutions reduced to 30-40% of the original volume showed that calcium phosphate had formed in solutions with a starting pH of 7.28 and 6.45. In solutions with pH 5.80 calcium oxalate crystals were observed with calcium phosphate.

Place, publisher, year, edition, pages
1999. Vol. 27, no 6, 409-416 p.
Keyword [en]
crystallization, calcium phosphate, calcium oxalate, distal tubule, macromolecules, promotion, inhibition, pH
National Category
Social Sciences
Identifiers
URN: urn:nbn:se:liu:diva-49909OAI: oai:DiVA.org:liu-49909DiVA: diva2:270805
Available from: 2009-10-11 Created: 2009-10-11 Last updated: 2017-12-12

Open Access in DiVA

No full text

Authority records BETA

Fornander, Anne-Marie

Search in DiVA

By author/editor
Fornander, Anne-Marie
By organisation
Faculty of Arts and SciencesDepartment of health and environment
In the same journal
Urological research
Social Sciences

Search outside of DiVA

GoogleGoogle Scholar

urn-nbn

Altmetric score

urn-nbn
Total: 31 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf