liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
An in vitro model for assessment of the biological activity of hepatocyte growth factor
Linköping University, Department of Clinical and Experimental Medicine, Infectious Diseases. Linköping University, Faculty of Health Sciences.
Linköping University, Department of Clinical and Experimental Medicine, Medical Microbiology. Linköping University, Faculty of Health Sciences.
Linköping University, Department of Clinical and Experimental Medicine, Medical Microbiology. Linköping University, Faculty of Health Sciences.
Linköping University, Department of Clinical and Experimental Medicine, Infectious Diseases. Linköping University, Faculty of Health Sciences.
Show others and affiliations
2007 (English)In: Growth Factors, ISSN 0897-7194, E-ISSN 1029-2292, Vol. 25, no 1, 33-40 p.Article in journal (Refereed) Published
Abstract [en]

Hepatocyte growth factor (HGF) is a multifunctional growth factor with potent wound-healing properties that functions in the healing of chronic injuries. However, there may be a loss of HGF activity in certain chronic cases; this might be indicated by the presence of high amounts of HGF in body fluids and by the elevated expression of the HGF receptor in tissue biopsies. In such cases, a reliable means of assessing the activity of endogenous HGF would be valuable in allowing clinicians to decide if treatment with HGF would be useful. In this study, we developed an in vitro wound assay that used a mouse skin epithelial cell line to evaluate the biological activity of HGF. We showed that HGF accelerated the motility of the epithelial cells in a dose-dependent fashion with high sensitivity and specificity. This in vitro assay might be used to determine the activity of both endogenous and recombinant HGF.

Place, publisher, year, edition, pages
2007. Vol. 25, no 1, 33-40 p.
Keyword [en]
Activity, Body fluids, HGF, In vitro, In vivo, Recombinant
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-50004DOI: 10.1080/08977190600997200OAI: oai:DiVA.org:liu-50004DiVA: diva2:270900
Available from: 2009-10-11 Created: 2009-10-11 Last updated: 2017-12-12Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Authority records BETA

Nayeri, FaribaHolmgren Peterson, KajsaPerskvist, NasrinForsberg, PiaPeterson, CurtSundqvist, Tommy

Search in DiVA

By author/editor
Nayeri, FaribaHolmgren Peterson, KajsaPerskvist, NasrinForsberg, PiaPeterson, CurtSundqvist, Tommy
By organisation
Infectious DiseasesFaculty of Health SciencesMedical MicrobiologyPharmacology
In the same journal
Growth Factors
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 96 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf