liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Bladder cooling reflex and external urethral sphincter activity in the anesthetized and awake guinea pig
Linköping University, Faculty of Health Sciences. Linköping University, Department of Clinical and Experimental Medicine, Cell Biology.
Medical College, Hunan Normal University, Changsha, Hunan 410006, China.
Medical College, Hunan Normal University, Changsha, Hunan 410006, China.
Medical College, Hunan Normal University, Changsha, Hunan 410006, China.
Show others and affiliations
2008 (English)In: Pflügers Archiv: European Journal of Physiology, ISSN 0031-6768, E-ISSN 1432-2013, Vol. 457, no 1, 61-66 p.Article in journal (Refereed) Published
Abstract [en]

A spinal bladder cooling reflex, triggered by cold receptors of transient receptor potential melastatin type in the bladder wall, has been identified in several mammals, including man. This reflex and its influence on the external urethral sphincter were further characterized in the urethane anesthetized and awake guinea pigs. A total of 214 bladder infusions were performed in the 12 animals. Compared to controls, cold fluid induced a significant decrease in the threshold volume for reflex bladder contractions (median 82%, p<0.01). Menthol induced a further decrease (median 50%), signifying a bladder cooling reflex. Detrusor-sphincter activities were dyssynergic during voidings triggered by cold or menthol infusions but were coordinated during control infusions. The bladder cooling reflex was suppressed and the sphincter activity synergic following cold infusions in the awake state. Thus, the bladder cooling reflex is under the active descending inhibitory control in intact, awake animals. © 2008 Springer-Verlag.

Place, publisher, year, edition, pages
2008. Vol. 457, no 1, 61-66 p.
Keyword [en]
Cooling reflex, EMG, Guinea pig, Urinary bladder, Wakefulness
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-50020DOI: 10.1007/s00424-008-0502-9OAI: oai:DiVA.org:liu-50020DiVA: diva2:270916
Available from: 2009-10-11 Created: 2009-10-11 Last updated: 2017-12-12

Open Access in DiVA

No full text

Other links

Publisher's full text

Authority records BETA

Jiang, ChongheLindström, Sivert

Search in DiVA

By author/editor
Jiang, ChongheLindström, Sivert
By organisation
Faculty of Health SciencesCell Biology
In the same journal
Pflügers Archiv: European Journal of Physiology
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 42 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf