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Early recovery from post-traumatic acute respiratory distress syndrome
Östergötlands Läns Landsting, Anaesthesiology and Surgical Centre, Department of Intensive Care UHL.
Department of Diagnostic Radiology, University Hospital Leipzig, Liebigstrasse 20, D-04103 Leipzig, Germany.
Surgical Intensive Care Unit, University Hospital Leipzig, Liebigstrasse 20, D-04103 Leipzig, Germany.
Department of Anaesthesiology and Intensive Care Medicine, University Hospital Leipzig, Liebigstrasse 20, D-04103 Leipzig, Germany.
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2006 (English)In: Clinical Physiology and Functional Imaging, ISSN 1475-0961, E-ISSN 1475-097X, Vol. 26, no 6, 376-379 p.Article in journal (Refereed) Published
Abstract [en]

Background: To present and discuss the rationale and possible benefits of timely alveolar recruitment in early post-traumatic acute respiratory distress syndrome. Methods: A 17-year-old patient who had sustained blunt thoracic trauma presented with severe hypoxaemia on admission and whole body computed tomography showed pulmonary contusion and substantial bilateral atelectasis. Oxygenation and lung mechanics did not improve with low tidal volume ventilation using high positive end-expiratory pressures (PEEPs). Therefore we applied an alveolar recruitment manoeuvre 7 h after admission. After alveolar recruitment, PEEP was titrated to the lowest level which prevented alveolar derecruitment. Results: Oxygenation and lung compliance improved rapidly and aeration of the entire lung was confirmed by computed tomography 27 h after the recruitment manoeuvre. The patient recovered completely and was discharged after 17 days. Conclusion: Although robust evidence is stilllacking, several lines of evidence suggest potential benefits of timely alveolar recruitment. Patients with early post-traumatic respiratory failure seem to most readily respond to alveolar recruitment manoeuvres and could thus benefit from the gain in functional lung volume and oxygenation. Moreover the probability of ventilator associated complications may be reduced. © 2006 The Authors Journal compilation 2006 Blackwell Publishing Ltd.

Place, publisher, year, edition, pages
2006. Vol. 26, no 6, 376-379 p.
Keyword [en]
Acute respiratory distress syndrome, Atelectasis, Positive pressure respiration, Thoracic injuries
National Category
Natural Sciences
URN: urn:nbn:se:liu:diva-50086DOI: 10.1111/j.1475-097X.2006.00702.xOAI: diva2:270982
Available from: 2009-10-11 Created: 2009-10-11 Last updated: 2012-01-06

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