liu.seSearch for publications in DiVA
Change search
ReferencesLink to record
Permanent link

Direct link
Prevention of chemotherapy- and radiotherapy-induced emesis: Results of the 2004 Perugia International Antiemetic Consensus Conference
Medical Oncology Division, Silvestrini Hospital, 06156S Andrea delle Fratte, Perugia, Italy.
Institut Multidisciplinaire d'Oncologie, Genolier, Switzerland.
Statistics Unit, L'Aquila, Italy.
Division of Nursing Science, Linkoping University, Linkoping, Sweden.
Show others and affiliations
2006 (English)In: Annals of Oncology, ISSN 0923-7534, Vol. 17, no 1, 20-28 p.Article, review/survey (Refereed) Published
Abstract [en]

Background: In the late 1990s, several professional organizations convened antiemetic guideline groups and published the findings of these expert panels. Each of these documents was based on analyses of the available published trials and provided nearly similar recommendations. Nonetheless, small differences in emetic risk categories and treatment recommendations led to confusion in antiemetics selection. With the emergence of new findings and agents since the guidelines were initially published, many of the oncology professional societies have updated the antiemetic guidelines. Materials and methods: A literature review up to March 2004 was carried out using MEDLINE with evaluation of the evidence by an expert panel composed of 23 oncology professionals in clinical medicine, medical oncology, radiation oncology, oncology nursing, statistics, pharmacy, medical policy and decision making, and pharmacology. The experts represented nine oncology professional societies and came from 11 different countries on four continents. Results: Recommendations on antiemetic regimens to prevent emesis induced by high, moderate, low and minimal risk chemotherapy were suggested as well as management of anticipatory emesis. Furthermore, recommendations for refractory emesis, emesis induced by high-dose chemotherapy and radiotherapy and for antiemetics in children receiving chemotherapy were elaborated. Conclusions: Recommendations about antiemetic prophylaxis in patients receiving treatment with chemo- and radiotherapy have been updated by representatives of nine oncological organizations. © 2005 European Society for Medical Oncology.

Place, publisher, year, edition, pages
2006. Vol. 17, no 1, 20-28 p.
Keyword [en]
5-HT3-receptor antagonists, Acute emesis, Aprepitant, Delayed emesis, Dexamethasone, Metoclopramide
National Category
Natural Sciences
URN: urn:nbn:se:liu:diva-50326DOI: 10.1093/annonc/mdj078OAI: diva2:271222
Available from: 2009-10-11 Created: 2009-10-11 Last updated: 2011-01-11

Open Access in DiVA

No full text

Other links

Publisher's full text
In the same journal
Annals of Oncology
Natural Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 35 hits
ReferencesLink to record
Permanent link

Direct link