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Intermittent injection of bupivacaine into the margin or the cavity after reduction mammaplasty
Linköping University, Faculty of Health Sciences. Linköping University, Department of Clinical and Experimental Medicine.
Linköping University, Faculty of Health Sciences. Linköping University, Department of Clinical and Experimental Medicine, Surgery . Östergötlands Läns Landsting, Reconstruction Centre, Department of Plastic Surgery, Hand surgery UHL.
2005 (English)In: Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery, ISSN 0284-4311, Vol. 39, no 4, 218-221 p.Article in journal (Refereed) Published
Abstract [en]

Twenty-seven operated women had postoperative intermittent injections of bupivacaine or saline for 24 hours after reduction mammaplasty. The injections were given five-hourly either subcutaneously along the submammary incision or deep into the wound. The patients were randomised into three groups of nine each: 5 ml bupivacaine 0.25% into the margin, 5 ml bupivacaine 0.25% into the cavity, and 5 ml physiological saline into the cavity. Postoperatively all patients received oral paracetamol and dextropropoxyphene. If additional analgesia was needed morphine was given intravenously. Total morphine consumption was significantly (p <0.03) lower in patients given bupivacaine into the margin (2.0 (0.9) mg) or into the cavity (2.4 (0.8) mg) compared with controls (6.9 (1.5) mg). VAS pain scores and vomiting did not differ among the three groups. Postoperative intermittent infusion of bupivacaine lowered morphine consumption after reduction mammaplasty, and the analgesic effect seemed to be independent of where the infusion was given. © 2005 Taylor & Francis.

Place, publisher, year, edition, pages
2005. Vol. 39, no 4, 218-221 p.
Keyword [en]
Bupivacaine, Nausea, Postoperative pain, Pre-emptive analgesia, Reduction mammaplasty
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-50422DOI: 10.1080/0284431051003139OAI: oai:DiVA.org:liu-50422DiVA: diva2:271318
Available from: 2009-10-11 Created: 2009-10-11 Last updated: 2011-01-12

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Holmgren, RafaelTarpila, Erkki

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Holmgren, RafaelTarpila, Erkki
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Faculty of Health SciencesDepartment of Clinical and Experimental MedicineSurgery Department of Plastic Surgery, Hand surgery UHL
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Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery
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