Meaning is often viewed as originating within an individual mind and then expressed by a combination of speech and gesture. In this article I present evidence from documented spontaneous interaction that supports the claim that speech and gesture should be viewed as complementary aspects of the on-going incremental determination of dialogic inter-subjective intentionality in communicative interaction. Speech and gesture relate brain with brain to enable meaning and mind. Embodied meaning is enacted through speech and gesture in interaction. Mind is viewed as embodied but distributed and emerges in the field created by interacting brains-and-bodies. An empirical research methodology for the study of speech and gesture in relation to mind and meaning in interaction is presented.