The Discovery of Cellular Immunity in the Atherosclerotic Plaque
2009 (English)In: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, ISSN 1079-5642, Vol. 29, no 11, 1714-1717 p.Article in journal (Refereed) Published
It is now generally accepted that atherosclerosis is an inflammatory/immune disease triggered by LDL accumulation in the artery wall. When discovering T cells and the molecular components of a cellular immune response, we proposed that atherosclerosis is an inflammatory process with an autoimmune component. This notion was met with general skepticism but has gained support from experimental and clinical studies. Here we describe some of the early studies that helped developing this concept.
Place, publisher, year, edition, pages
2009. Vol. 29, no 11, 1714-1717 p.
athersclerosis, immunity, inflammation, cytokines, T cells, macrophages
National CategoryMedical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-51486DOI: 10.1161/ATVBAHA.108.179713OAI: oai:DiVA.org:liu-51486DiVA: diva2:275302