liu.seSearch for publications in DiVA
Change search
ReferencesLink to record
Permanent link

Direct link
Cranial CT for diagnosis of intracranial complications in adult and pediatric patients during ECMO: Clinical benefits in diagnosis and treatment
Karolinska universitetssjukhuset, Stockholm.
Karolinska universitetssjukhuset, Stockholm.
Karolinska University Hospital.ORCID iD: 0000-0001-9531-7892
Karolinska universitetssjukhuset, Stockholm.
Show others and affiliations
2007 (English)In: Academic Radiology, ISSN 1076-6332, E-ISSN 1878-4046, Vol. 14, no 1, 62-71 p.Article in journal (Refereed) Published
Abstract [en]

RATIONALE AND OBJECTIVES: To evaluate the clinical utility of cranial computed tomography (CT) in pediatric and adult patients during ongoing extracorporeal membrane oxygenation (ECMO) treatment from acute respiratory failure and to assess the frequency of intracranial hemorrhage (ICH) and infarction during the treatment. MATERIALS AND METHODS: The medical records of 123 consecutive patients, 54 children (ages 3 months-17 years) and 69 adults (ages 18-62 years), treated with ECMO over a 10-year period were searched for cranial CT performed during ECMO. Indications for CT, CT findings, impact on clinical management, and patient outcome were noted. In addition, all CT scans were reviewed for the frequency of ICH or infarction. RESULTS: Seventy-eight patients had cranial CT while on ECMO. ICH or cerebral infarction were detected in 45 (37%) of the 123 patients. Eighteen patients (15%) had focal hemorrhage, 11 (9%) focal infarction, and 16 (13%) general brain edema. In 16 of the 45 patients, the CT findings were decisive to withdraw the ECMO treatment. Five patients were weaned from ECMO, and in four patients the findings motivated cranial surgery during ECMO. In the remaining 20 patients with less extended intracranial pathology, the ECMO treatment was continued with high survival. CONCLUSION: Cranial CT has an important role during ECMO treatment to reveal or exclude severe intracranial complications where ECMO treatment should be discontinued. Less severe complications have a favorable prognosis with continued treatment. Our study suggests an underreporting of intracranial complications in adults and pediatric patients on ECMO because of low utilization of neuroimaging.

Place, publisher, year, edition, pages
Netherlands: Elsevier BV , 2007. Vol. 14, no 1, 62-71 p.
Keyword [en]
Extracorporeal membrane oxygenation (ECMO), computed tomography (CT), intracharanial hemorrhage (ICH), cerebral infarction
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-51561DOI: 10.1016/j.acra.2006.10.004PubMedID: 16767398OAI: diva2:275717
Available from: 2009-11-06 Created: 2009-11-06 Last updated: 2013-09-03

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Ringertz, Hans
In the same journal
Academic Radiology
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 25 hits
ReferencesLink to record
Permanent link

Direct link