Translating Electronic Currents to Precise Acetylcholine-Induced Neuronal Signaling Using an Organic Electrophoretic Delivery Device
2009 (English)In: Advanced Materials, ISSN 0935-9648, E-ISSN 1521-4095, Vol. 21, no 44, 4442- p.Article in journal (Refereed) Published
A miniaturized organic electronic ion pump (OEIP) based on conjugated polymers is developed for delivery of positively charged biomolecules. Characterization shows that applied voltage can precisely modulate the delivery rate of the neurotransmitter acetylcholine. The capability of the device is demonstrated by convection-free, spatiotemporally resolved delivery of acetylcholine via a 10 mu m channel for dynamic stimulation of single neuronal cells.
Place, publisher, year, edition, pages
2009. Vol. 21, no 44, 4442- p.
Engineering and Technology
IdentifiersURN: urn:nbn:se:liu:diva-52901DOI: 10.1002/adma.200900187OAI: oai:DiVA.org:liu-52901DiVA: diva2:285756