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Electroactive Surfaces Based on Conducting Polymers for Controlling Cell Adhesion, Signaling, and Proliferation
Linköping University, Department of Science and Technology, Physics and Electronics. Linköping University, The Institute of Technology. (Organisk elektronik)ORCID iD: 0000-0002-2071-7768
Linköping University, Department of Science and Technology, Physics and Electronics. Linköping University, The Institute of Technology. (Organisk elektronik)
Karolinska Insitutet, Inst. för Neurovetenskap.
Linköping University, Department of Science and Technology, Physics and Electronics. Linköping University, The Institute of Technology. (Organisk elektronik)
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2009 (English)In: Transducers 2009: The 15th International Conferece on solid-State Sensors, Actuators & Microsystems, IEEE conference proceedings, 2009, 1778-1781 p.Conference paper, Published paper (Other academic)
Abstract [en]

We report on a variety of electroactive surfaces for the control of in vitro cell adhesion, proliferation, and stimulation. Planar cell culture substrates have been coated with the conducting polymer PEDOT and by switching the redox state, adhesion and proliferation of MDCK epithelial cells was controlled as well as stem cell seeding density. Electronically active 3D-scaffolds based on electrospun PET nano-fibers coated with PEDOT have been used as a substrate to culture SH-SY5Y neuroblastoma cells and to induce Ca2+ signaling. Finally, we report on micromechanical stimulation of cells using an electroactive topography surface based on micropattened polypyrrole.

Place, publisher, year, edition, pages
IEEE conference proceedings, 2009. 1778-1781 p.
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Natural Sciences
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URN: urn:nbn:se:liu:diva-53032DOI: 10.1109/SENSOR.2009.5285718ISBN: 978-1-4244-4193-8 (print)OAI: oai:DiVA.org:liu-53032DiVA: diva2:286489
Conference
15th International Conference on Solid-State Sensors, Actuators and Microsystems; Denver, CO; United States
Available from: 2010-01-14 Created: 2010-01-14 Last updated: 2017-02-03

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Jager, EdwinBolin, MariaWang, XBerggren, Magnus

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