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An Organic Electronic Ion Pump to Regulate Intracellular Signaling at High Spatiotemporal Resolution
Linköping University, Department of Science and Technology, Physics and Electronics. Linköping University, The Institute of Technology. (Organisk elektronik)ORCID iD: 0000-0002-2799-3490
Linköping University, Department of Science and Technology, Physics and Electronics. Linköping University, The Institute of Technology. (Organisk elektronik)ORCID iD: 0000-0002-2071-7768
Linköping University, Department of Science and Technology, Physics and Electronics. Linköping University, The Institute of Technology. (Organisk elektronik)ORCID iD: 0000-0002-9845-446X
Karolinska Institutet, Inst för Neurovetenskap.
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2009 (English)In: Transducers 2009: The 15th international conference on Solid-State Sensor, Actuators and Microsystems, IEEE conference proceedings, 2009, 1790-1793 p.Conference paper, Published paper (Other academic)
Abstract [en]

Current technologies for cell stimulation suffer from a variety of drawbacks. Indeed, precise, localized, and minimally disruptive machine-to-cell interfacing is difficult to achieve. Here we present the organic electronic ion pump (OEIP), a polymer-based delivery system exhibiting high spatial, temporal, and dosage precision. Based on electrophoretic transport of positively charged species, the OEIP can deliver - with high precision - an array of biologically relevant substances without fluid flow, thus eliminating convective disturbance of the target system's environment. We discuss our results to date, including oscillatory delivery profiles and stimulation of neuronal cells in vitro, as well as our ongoing work.

Place, publisher, year, edition, pages
IEEE conference proceedings, 2009. 1790-1793 p.
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Natural Sciences
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URN: urn:nbn:se:liu:diva-53036DOI: 10.1109/SENSOR.2009.5285721ISBN: 978-1-4244-4193-8 (print)OAI: oai:DiVA.org:liu-53036DiVA: diva2:286505
Available from: 2010-01-14 Created: 2010-01-14 Last updated: 2017-02-03

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Simon, DanielJager, EdwinTybrandt, KlasBerggren, Magnus

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  • apa
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