liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Newly found prostate-bladder neural reflex in rats--possible mechanism for      voiding dysfunction associated with prostatitis/pelvic pain
Southwest Hospital, Third Military Medical University.
Hunan Normal University Medical College. (Sivert Lindström)
Southwest Hospital, Third Military Medical University.
Southwest Hospital, Third Military Medical University.
Show others and affiliations
2009 (English)In: Urology, ISSN 0090-4295, E-ISSN 1527-9995, Vol. 74, no 6, 1365-1369 p.Article in journal (Refereed) Published
Abstract [en]
Objectives

To demonstrate the existence of a prostate-bladder neural reflex that might help clarify a neurologic mechanism for voiding dysfunction associated with chronic prostatitis/chronic pelvic pain syndrome.

Methods

Experiments were performed on anesthetized adult male Wistar rats. Repeated cystometry was used to study the changes in urinary bladder behavior induced by injecting formalin into the prostate. The pathway of a prostate-bladder reflex was identified by recording the electromyographic (EMG) response of the detrusor to electrical stimulation of the prostate, after saline or lidocaine injections into the prostate, and transection of the prostate nerves.

Results

Intraprostatic formalin injection induced significant changes in the parameters of cystometry. Electrical stimulation of the prostate consistently evoked a bladder EMG response. Intraprostatic lidocaine injection increased the delay and reduced the amplitude of this EMG response. The bladder EMG response was not affected by transection of the cervical spinal cord nor by just cutting the sympathetic chain; however, it was suppressed by resection of the sympathetic chain and by transection of the ipsilateral L6-S3 nerve roots.

Conclusions

A prostate-bladder reflex is proposed, and the lumbosacral spinal cord is assumed to be the primary center of the reflex. These findings might help determine the therapeutic approach to voiding dysfunction in patients with chronic prostatitis/chronic pelvic pain syndrome.

Place, publisher, year, edition, pages
2009. Vol. 74, no 6, 1365-1369 p.
Identifiers
URN: urn:nbn:se:liu:diva-53158DOI: 10.1016/j.urology.2009.02.063OAI: oai:DiVA.org:liu-53158DiVA: diva2:287000
Available from: 2010-01-16 Created: 2010-01-16 Last updated: 2017-12-12

Open Access in DiVA

No full text

Other links

Publisher's full text

Authority records BETA

Jiang, Chonghe

Search in DiVA

By author/editor
Jiang, Chonghe
In the same journal
Urology

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 34 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf