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Evidence for anti-osteoporosis therapy in acute fracture situations-Recommendations of a multidisciplinary workshop of the International Society for Fracture Repair
Schulthess Klin Zurich.
Childrens Hospital, Westmead, NSW Australia .
University of Derby.
SA Pathol and Hanson Institute.
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2010 (English)In: BONE, ISSN 8756-3282, Vol. 46, no 2, 267-271 p.Article in journal (Refereed) Published
Abstract [en]

The International Society for Fracture Repair convened a multidisciplinary workshop to assess the current evidence around the interaction between anti-osteoporosis drugs and the healing of incident fractures, with a view to making recommendations for clinical practice. The consensus was that there is no evidence-based reason to withhold anti-resorptive therapy while a fracture heals, whether or not the patient was taking such therapy when the fracture occurred. The workshop also considered existing models of service provision for secondary prevention and concluded that the essential ingredient for reliable delivery is the inclusion of a dedicated coordinator role. Several unresolved issues were defined as subjects for further research, including the question of whether continuous long-term administration of anti-resorptives may impair bone quality. The rapidly changing area requires re-assessment of drugs and their interaction with fracture healing in the near future.

Place, publisher, year, edition, pages
2010. Vol. 46, no 2, 267-271 p.
Keyword [en]
Fracture healing, Osteoporosis, Drugs, Drug interaction
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-54264DOI: 10.1016/j.bone.2009.10.004ISI: 000274702800003OAI: oai:DiVA.org:liu-54264DiVA: diva2:302276
Available from: 2010-03-05 Created: 2010-03-05 Last updated: 2010-03-05

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Aspenberg, Per

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Orthopaedics and Sports Medicine Faculty of Health SciencesDepartment of Orthopaedics Linköping
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