Environmentally Sensitive Fluorescent Sensors Based on Synthetic Peptides
2010 (English)In: SENSORS, ISSN 1424-8220, Vol. 10, no 4, 3126-3144 p.Article, review/survey (Refereed) Published
Biosensors allow the direct detection of molecular analytes, by associating a biological receptor with a transducer able to convert the analyte-receptor recognition event into a measurable signal. We review recent work aimed at developing synthetic fluorescent molecular sensors for a variety of analytes, based on peptidic receptors labeled with environmentally sensitive fluorophores. Fluorescent indicators based on synthetic peptides are highly interesting alternatives to protein-based sensors, since they can be synthesized chemically, are stable, and can be easily modified in a site-specific manner for fluorophore coupling and for immobilization on solid supports.
Place, publisher, year, edition, pages
Molecular Diversity Preservation International (MDPI) , 2010. Vol. 10, no 4, 3126-3144 p.
peptide biosensors, environmentally-sensitive fluorophore
Engineering and Technology
IdentifiersURN: urn:nbn:se:liu:diva-56446DOI: 10.3390/s100403126ISI: 000277159700034OAI: oai:DiVA.org:liu-56446DiVA: diva2:319266