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Aligned carbon nanotubes on quartz substrate for liquid gated biosensing
School of Materials Science and Engineering. Nanyang Technological University, Singapore 639798, Singapore.
School of Materials Science and Engineering. Nanyang Technological University, Singapore 639798, Singapore.
School of Materials Science and Engineering. Nanyang Technological University, Singapore 639798, Singapore.
School of Materials Science and Engineering. Nanyang Technological University, Singapore 639798, Singapore.
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2010 (English)In: Biosensors and Bioelectronics, Vol. 25, 1989-1993 p.Article in journal (Refereed) Published
Abstract [en]

A facile and high performance biosensing platform using aligned carbon nanotubes on quaratz substrate is reported in this communication. Single walled carbon nanotubes are grown on quartz substrates by a chemical vapor despotition process and are characterized with field emission scanning electron microscopy and atomic force microscopy in order to verify the quality of the material. The quartz substrate is then directly used as a biosensor in a field effect transistor configuration. In order to demonstrate the sensing capabilities of the fabricated sensor devices, electronic detection of prostate specific antigen, a potential cancer biomarker, is carried out by adopting liquid gated configuration. A conductivity change due to the specific binding of target antigen with the immobilized receptor andtibody demonstrates the sensing capabilities of the fabricated device. Sub-nM detection sensitivities have been obtained using the adopted direct immunoassay approach, which shows that the device responds to clinically relevant concentration regimes

Place, publisher, year, edition, pages
Elsevier , 2010. Vol. 25, 1989-1993 p.
Keyword [en]
Biosensor. Single walled carbon nanotube. Field effect transistor. Liquid gating
National Category
Analytical Chemistry
Identifiers
URN: urn:nbn:se:liu:diva-56472DOI: 10.1016/j.bios.2010.01.009OAI: oai:DiVA.org:liu-56472DiVA: diva2:319725
Available from: 2010-05-19 Created: 2010-05-18 Last updated: 2011-03-23

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Liedberg, Bo

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Analytical Chemistry

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