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Olfactory sensitivity in CD-1 mice for six L- and D amino acids
Linköping University, Department of Physics, Chemistry and Biology.
2010 (English)Independent thesis Advanced level (degree of Master (Two Years)), 40 credits / 60 HE creditsStudent thesis
Abstract [en]

The olfactory sensitivity of five male CD-1 mice (Mus musculus) for six amino acids was determined using an operant conditioning paradigm. All animals significantly distinguished dilutions as low as 0.01 mM L-cysteine, 3.3 mM L-methionine, 10 mM L-proline, 0.03 mM D-cysteine, 0.3 mM D-methionine and 10 mM D-proline from the odorless solvent, with individual animals displaying even lower detection thresholds. Among the three different L-forms of the amino acids the mice were most sensitive for cysteine and least sensitive for proline, and among the three D-forms the animals displayed a lower sensitivity for D-proline compared to D-cysteine and D-methionine. A comparison between the present data and results obtained with other species showed that the CD-1 mice displayed a higher sensitivity than human subjects and spider monkeys with three (L-Cysteine, D-cysteine and L-proline) of the six amino acids. Results from this report support the idea that the number of functional olfactory receptor genes is not suitable to predict a species’ olfactory sensitivity.

Place, publisher, year, edition, pages
2010. , 29 p.
Keyword [en]
Amino acid, Olfaction, CD-1 mice, olfactory receptor genes and sulphur- containing group.
National Category
Biological Sciences
URN: urn:nbn:se:liu:diva-56783ISRN: LITH-IFM-A-EX--2351--SEOAI: diva2:322219
2010-05-28, Planck, Linköpings university, Physics house, 09:50 (English)
Life Earth Science
Available from: 2010-06-11 Created: 2010-06-04 Last updated: 2011-05-18Bibliographically approved

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Wallén, Helena
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Department of Physics, Chemistry and Biology
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